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Contact inhibition means that


A) there are more chromosomes within the nucleus than there should be.
B) cells are able to divide without the presence of stimulatory growth factors.
C) cells only divide a certain specified number of times and then quit.
D) when cells come in contact with a neighbor, they stop dividing.
E) cells have gained the ability to invade lymphatic and blood vessels.

F) C) and E)
G) A) and E)

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When should screening for colorectal cancer begin?


A) in 20s
B) in 30s
C) in 40s
D) in 50s
E) in 60s

F) B) and E)
G) None of the above

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D

What type of cancer causes the most deaths in males?


A) prostate
B) lung and bronchus
C) colon and rectum
D) pancreas
E) esophagus

F) D) and E)
G) A) and C)

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Which of the following characteristics is not associated with metastasis?


A) The internal cytoskeleton is disorganized.
B) The cancer cells lack intact actin filament bundles.
C) Invasive cancer cells are sperm-shaped.
D) Cancer cells produce proteinase enzymes.
E) The low oxygen content in the middle of a tumor may turn on genes for angiogenesis.

F) All of the above
G) A) and D)

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The ends of the chromosomes are "capped" with special repetitive DNA sequences called


A) radiata.
B) telomeres.
C) centromeres.
D) oncogenes.
E) suppressor genes.

F) None of the above
G) B) and C)

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Explain what the acronym CAUTION means in regard to the warning signs of cancer.

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C = change in bowel or bladder habits A = a sore that does not heal U = unusual bleeding or discharge T = thickening or difficulty in swallowing I = indigestion or difficulty in swallowing O = obvious change in wart or mole N = nagging cough or hoarseness

Which two tests are done for prostate cancer?


A) mammography, fecal occult blood test
B) digital rectal examination, Pap test
C) PSA, testicle self-examination
D) digital rectal examination, PSA
E) testicle self-examination, fecal occult blood test

F) C) and D)
G) B) and C)

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Which of the following is not a type of chemotherapy?


A) alkylating agents
B) antimetabolites
C) antitumor antibiotics
D) bone marrow transplants
E) mitotic inhibitors

F) A) and B)
G) A) and C)

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Which of the following is not a type of proto-oncogene?


A) the gene for cyclin D
B) growth factor receptor genes
C) the gene that codes for Ras proteins
D) growth factor genes
E) the gene for p53

F) A) and B)
G) A) and C)

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How often should a woman do a shower self-examination of her breasts for lumps, knots, or changes?


A) daily
B) once a week
C) once a month
D) once every 6 months
E) once a year

F) A) and D)
G) A) and B)

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If a tumor suppressor gene becomes mutated, which of the following is not true?


A) Apoptosis is less likely to occur.
B) The cell cycle continues when it should not.
C) A "gain-of function" mutation has occurred.
D) Genes that encode enzymes that repair DNA are not turned on.
E) Genes that stop the cell cycle are not turned on.

F) C) and D)
G) A) and E)

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C

Which of the following is not a characteristic of cancer cells that distinguishes it from normal cells?


A) Cancer cells lack differentiation.
B) Cancer cells have abnormal nuclei.
C) Cancer cells utilize mitosis to divide.
D) Cancer cells have an unlimited potential to replicate.
E) Cancer cells form tumors.

F) A) and E)
G) B) and E)

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Both heredity and environmental risk factors come into play in the development of cancer.

A) True
B) False

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Which of the following is a side effect of radiation therapy that is not also a side effect of chemotherapy?


A) nausea, vomiting
B) dry, red, irritated skin and/or blisters
C) diarrhea
D) fatigue and weakness
E) weight loss and hair loss

F) C) and D)
G) A) and B)

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Which of the following tests is not used to screen for colon cancer?


A) blood test
B) digital examination
C) flexible sigmoidoscopy
D) fecal occult blood test
E) double-contrast barium enema

F) C) and D)
G) A) and B)

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What type of test is a CEA test?


A) self-examination
B) a type of prostate cancer test
C) a type of cervical cancer test
D) a genetic test
E) a tumor marker test

F) A) and B)
G) A) and C)

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Which of the following is not a type of ionizing radiation?


A) ultraviolet radiation
B) radon gas
C) nuclear fuel
D) X-rays
E) none of these are ionizing radiation

F) A) and E)
G) B) and D)

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Antiangiogenic drugs cause cytotoxic T cells to attack tumor cells.

A) True
B) False

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Which of the following is not one of the things to watch for in a mole?


A) asymmetry
B) irregular border
C) a solid color, usually brown
D) larger than 6 mm
E) elevated above the skin surface

F) D) and E)
G) A) and E)

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Hodgkin lymphomas develop from


A) cells of the liver and spleen.
B) all types of white blood cells.
C) B or T cells.
D) mutated B cells.
E) bladder epithelial cells.

F) All of the above
G) C) and D)

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