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During organ transplant,which feature is the most important to recognize?


A) The difference between the MHC proteins of the donor and the recipient.
B) The difference between the blood types of the donor and the recipient.
C) The similarities between the blood types of the donor and the recipient.
D) The type of organ being transplanted.
E) The age of the recipient of the transplanted organ.

F) B) and D)
G) A) and B)

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Which of the following health problems are likely to occur if a person is unable to form the IgE antibodies?


A) The person would have problems defending themselves against parasitic worm infections as well as lacking an immediate allergic response.
B) The person would be unable to activate the compliment.
C) Pathogens would be able to attach to their epithelial cells much easier.
D) They would be unable to have their cells clump.
E) Their B cells would be unable to respond to antigens.

F) B) and E)
G) B) and D)

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In order to decrease the effects of inflammation,you would take what type of medication?


A) antihistamine
B) vaccine
C) interferon
D) immunoglobulin
E) thromboplastin activator

F) None of the above
G) A) and B)

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Most antibodies found in the blood belong to what class of immunoglobulins?


A) IgA
B) IgD
C) IgE
D) IgG
E) IgM

F) B) and C)
G) A) and E)

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In the later 1800s,the brilliant French chemist Louis Pasteur worked with chicken cholera,passing the disease agent from sick to healthy chickens.He suspended his research and went on vacation for several weeks.When he returned,the old cholera culture he gave to healthy chickens failed to kill them.He assumed his culture was bad and injected these same chickens with a fresh culture of chicken cholera.These chickens remained healthy while new chickens injected with the fresh culture of chicken cholera rapidly became sick and died.From our current knowledge of immunity,how would these observations be explained?


A) Pasteur had accidentally discovered a strain of chickens that had natural immunity.
B) His first disease culture had weakened over time and stimulated the development of active immunity.
C) His first disease culture had weakened over time and the chickens developed a form of passive immunity.
D) The chickens apparently had better B cells for development of more effective antibodies.
E) The first set of chickens served as a control group to the second set that showed the development of antibodies.

F) A) and E)
G) B) and C)

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Earlier in the history of Western medicine,surgeons did not know the immune function of the thymus gland and it was sometimes removed in children.What symptoms would you now predict these patients might display afterward?


A) increased inflammatory and allergic responses to foreign material including viruses
B) reduced ability to recognize foreign material and distinguish it from body proteins
C) serious problems following receiving blood transfusions of any type of blood
D) complete rejection of all normal body tissues
E) failure to produce any white blood cells

F) A) and E)
G) A) and D)

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Which of the following is NOT true of both T cells and B cells?


A) They are both lymphocytes.
B) They both pass through the thymus.
C) They both function in immunity.
D) They both are specific.
E) They both originated in bone marrow.

F) B) and E)
G) A) and B)

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Which lymphatic duct will drain the abdomen?


A) lymph capillaries
B) right lymphatic duct
C) left lymphatic duct
D) thoracic duct
E) inguinal duct

F) B) and C)
G) A) and E)

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Which of the following is true about the clonal selection theory?


A) An antigen selects certain B cells to produce a clone of plasma cells.
B) An antibody stimulates the multiplication of B cell antigens against it.
C) T cells select those B cells that should produce antibodies regardless of antigens.
D) T cells suppress all those B cells except the ones that should multiply and divide.
E) One B cell will give rise to plasma cells that produce antibodies against several antigens.

F) B) and E)
G) B) and C)

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Which is NOT part of a description of an antibody molecule?


A) contains a constant and a variable region on each chain
B) forms an X-shaped protein molecule
C) contains an antigen-binding site on each arm
D) contains two light chains and two heavy chains
E) contains hypervariable regions where antigens bind

F) A) and D)
G) B) and D)

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The AIDS virus attacks


A) helper T cells.
B) suppressor T cells.
C) cytotoxic T cells.
D) memory T cells.
E) B cells.

F) All of the above
G) None of the above

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When you have been bitten by a highly venomous snake and received a dose of venom sufficient to kill several people,you do not have the time to build up your own immunity over the next week.However,hospitals carry "antivenom" made from injecting horses with small-to-larger dosages of snake venom,and then harvesting the antibodies from the horse plasma.This is a case of


A) passive immunity.
B) active immunity.
C) developing an inflammatory response to increase the IgG production.
D) high levels of complement.
E) high levels of interferon.

F) A) and D)
G) C) and D)

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Which protein forms pores in bacterial cell membranes?


A) interferon
B) cytokines
C) histamine
D) complement
E) thrombin

F) A) and E)
G) A) and D)

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The clonal selection theory states that


A) all B cells are exact clones of one another.
B) all T cells are exact clones of one another.
C) a B or T cell is activated by binding to/recognizing an antigen, then that cell will be cloned into cells that recognize the same antigen.
D) when a B or T cell is stimulated by encountering the correct antibody, it divides to form a clone of cells that will respond to the same antibody.
E) T cells are stimulated by B cells to divide and form plasma cells, which secrete antibodies.

F) B) and C)
G) C) and D)

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Which of the following is specifically responsible for antibody-mediated immunity?


A) T cell
B) B cell
C) platelets
D) RBC
E) complement

F) A) and D)
G) A) and C)

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Which of the following is NOT an example of innate immunity?


A) natural killer cells
B) complement
C) inflammation
D) histamine
E) plasma cells

F) B) and E)
G) A) and D)

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Tissue rejection following organ transplantation is due to all of the following except


A) MHC incompatibility between donor and recipient.
B) transplantation of tissues from one part of the body to another in the same person.
C) the destruction of transplanted tissue by the immune system.
D) B cells and plasma cells that do not recognize the transplanted tissue as 'self'.
E) T cells that do not recognize the transplanted tissue as 'self'.

F) A) and B)
G) D) and E)

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Xenotransplantation is the use of animal organs instead of human organs in transplant patients.Scientists are considering using dogs as organ donors because they have long been domesticated by humans.

A) True
B) False

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What are the two most common applications of cytokine therapies?


A) stimulation of blood cells and treatment of cancer
B) stimulation of blood cells and treatment of HIV
C) treatment of cancer and HIV
D) production of antibodies
E) providing immunization against various diseases

F) A) and D)
G) C) and D)

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The larger lymphatic vessels are most similar in structure to


A) arteries.
B) cardiovascular veins.
C) capillaries.
D) intestinal villi.
E) nephron.

F) A) and B)
G) A) and C)

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