Question 1

An antiviral that is a guanine analog would have an antiviral mode of action that

Accepted Answer

A)  blocks penetration.
B)  blocks transcription and translation.
C)  inhibits DNA synthesis.
D)  blocks maturation.
E)  bonds to ergosterol in the cell membrane.F) C) and D)
G) B) and D)

Question 2

Which of the following is not a mode of action of antiviral drugs?

Accepted Answer

A)  block penetration
B)  block transcription and translation
C)  inhibit DNA synthesis
D)  block maturation
E)  bond to ergosterol in the cell membraneF) None of the above
G) D) and E)

Question 3

Which of these drugs has the most narrow-spectrum activity?

Accepted Answer

A)  tetracycline
B)  isoniazid
C)  erythromycin
D)  aminoglycosides
E)  cephalosporinsF) A) and C)
G) A) and B)

Question 4

Side effects that occur in patient tissues while they are on antimicrobial drugs include all of the following except

Accepted Answer

A)  development of resistance to the drug.
B)  hepatotoxicity.
C)  nephrotoxicity.
D)  diarrhea.
E)  deafness.F) D) and E)
G) B) and E)

Question 5

Which group are the key drugs used to treat Hansen's disease (leprosy) ?

Accepted Answer

A)  sulfonamides
B)  sulfones
C)  fluoroquinolones
D)  polymyxins
E)  streptomycesF) A) and C)
G) None of the above

Question 6

Which of the following antibacterial drug groups does not target protein synthesis?

Accepted Answer

A)  oxazolidinones
B)  macrolides
C)  aminoglycosides
D)  sulfonamides
E)  tetracyclinesF) B) and D)
G) B) and C)

Question 7

Alexander Fleming had been running tests using Staphylococcus,and left some plates out to incubate.Evidently,after returning to his lab after the weekend,he found that Penicillium mold was growing on his agar plates containing the growth of Staphylococcus.Looking more closely,he found a large,clear area around the mold colony where Staphylococcus colonies did not grow.Given this situation,a valid hypothesis would be that:

Accepted Answer

A)  The Staphylococcus was being inhibited by the Penicillium mold.
B)  The Penicillium mold was being killed by the Staphylococcus.
C)  The bacteriological medium being used in the plates was somehow inhibitory to the Staphylococcus growth.
D)  The room temperature incubation was inhibitory to the growth of Staphylococcus.E) A) and B)
F) A) and C)

Question 8

Each of the following contributes to emerging drug resistance except

Accepted Answer

A)  overuse of antibiotics.
B)  improper use of antibiotics.
C)  multiple drug therapy.
D)  ingestion of antibiotics with animal feed.
E)  addition of antibiotics to common household products.F) B) and E)
G) A) and B)

Question 9

Mebendazole,thiabendazole,and ivermectin are drugs used to treat _____ infections.

Accepted Answer

A)  bacterial
B)  fungal
C)  protozoan
D)  helminthic
E)  viralF) B) and E)
G) A) and C)

Question 10

Which drug is used to treat cases of tuberculosis?

Accepted Answer

A)  penicillin G
B)  vancomycin
C)  tetracycline
D)  synercid
E)  isoniazidF) All of the above
G) A) and D)

Question 11

Substances that are naturally produced by certain microorganisms that can inhibit or destroy bacteria are called

Accepted Answer

A)  antibiotics.
B)  narrow-spectrum drugs.
C)  semisynthetic drugs.
D)  synthetic drugs.
E)  broad-spectrum drugs.F) A) and D)
G) A) and C)

Question 12

Which antimicrobial does not interfere with protein synthesis?

Accepted Answer

A)  aminoglycosides
B)  tetracyclines
C)  erythromycin
D)  trimethroprim
E)  chloramphenicolF) A) and E)
G) A) and B)

Question 13

The patient has a staphylococcal infection of the blood,a septicemia--very serious and possibly deadly.As the doctor,you would like to prescribe a relatively non-toxic and inexpensive drug out of the cephalosporin family.However,if the patient harbors a strain of Staphylococcus that is resistant to a variety of antibiotics,you would prefer to use vancomycin-- which is highly effective against Staphylococcus.Which of the following explains why the cephalosporin drug is preferred for use over the vancomycin?

Accepted Answer

A)  You would rather give an inexpensive drug to save the family money.
B)  You really do not know that much about vancomycin,so you would rather go with a drug that you can find out more about.
C)  Vancomycin is very toxic,and the Staphylococcus strain could become resistant leaving no back-up drugs with which to treat the infection.
D)  Vancomycin is one of the most selectively toxic drugs there is,so you would prefer one that has a more broad-spectrum effect.E) A) and B)
F) All of the above

Question 14

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B,then pathogen A will have a/n _____ zone of inhibition compared to pathogen B.

Accepted Answer

A)  smaller
B)  equal
C)  largerD) B) and C)
E) A) and B)

Question 15

Sulfonamides

Accepted Answer

A)  interfere with elongation of peptidoglycan.
B)  are metabolic analogs of PABA and block folic acid synthesis.
C)  attach to the 30S ribosomal subunit and disrupt protein synthesis.
D)  damage cell membranes.
E)  block peptidases that cross-link glycan molecules.F) D) and E)
G) C) and D)

Question 16

Bacteria can have a natural resistance to a drug which they have never been exposed.

Accepted Answer

A) True 
 B)False

Question 17

The _____ are drugs that deposit in developing teeth and cause a permanent brown discoloration.

Accepted Answer

A)  streptomycins
B)  cephalosporins
C)  macrolides
D)  tetracyclines
E)  penicillinsF) C) and D)
G) A) and C)

Question 18

The cellular basis for bacterial resistance to antimicrobials include

Accepted Answer

A)  bacterial chromosomal mutations.
B)  synthesis of enzymes that alter drug structure.
C)  prevention of drug entry into the cell.
D)  alteration of drug receptors on cell targets.
E)  All of the choices are correct.F) B) and E)
G) A) and D)

Question 19

Drugs that insert on the _____ ribosomal subunit prevent peptide bond formation or inhibit translocation of the subunit during translation.

Accepted Answer

A)  30S
B)  40S
C)  50S
D)  60S
E)  70SF) A) and C)
G) C) and D)

Question 20

Sulfa drugs work on

Accepted Answer

A)  nucleic acid biosynthesis.
B)  ribosome biosynthesis.
C)  peptidoglycan biosynthesis.
D)  folic acid biosynthesis.E) All of the above
F) B) and D)

Exam 12: Drugs, Microbes, host-The Elements of Chemotherapy

Correct Answer
verified

Bacteria can have a natural resistance to a drug which they have never been exposed.

Correct Answer
verified

Sulfonamides

Correct Answer
verified

The cellular basis for bacterial resistance to antimicrobials include

Correct Answer
verified

Which group are the key drugs used to treat Hansen's disease (leprosy) ?

Correct Answer
verified

The _____ are drugs that deposit in developing teeth and cause a permanent brown discoloration.

Correct Answer
verified

Which of the following is not a mode of action of antiviral drugs?

Correct Answer
verified

Which antimicrobial does not interfere with protein synthesis?

Correct Answer
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Drugs that insert on the _____ ribosomal subunit prevent peptide bond formation or inhibit translocation of the subunit during translation.

Correct Answer
verified

Which of the following antibacterial drug groups does not target protein synthesis?

Correct Answer
verified

An antiviral that is a guanine analog would have an antiviral mode of action that

Correct Answer
verified

Substances that are naturally produced by certain microorganisms that can inhibit or destroy bacteria are called

Correct Answer
verified

Mebendazole,thiabendazole,and ivermectin are drugs used to treat _____ infections.

Correct Answer
verified

Which drug is used to treat cases of tuberculosis?

Correct Answer
verified

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B,then pathogen A will have a/n _____ zone of inhibition compared to pathogen B.

Correct Answer
verified

Side effects that occur in patient tissues while they are on antimicrobial drugs include all of the following except

Correct Answer
verified

Each of the following contributes to emerging drug resistance except

Correct Answer
verified

Which of these drugs has the most narrow-spectrum activity?

Correct Answer
verified

Correct Answer
verified

Sulfa drugs work on

Correct Answer
verified

Exam 12: Drugs, Microbes, host-The Elements of Chemotherapy

Correct AnswerverifiedShow Answer

Bacteria can have a natural resistance to a drug which they have never been exposed.

Correct AnswerverifiedShow Answer

Sulfonamides

Correct AnswerverifiedShow Answer

The cellular basis for bacterial resistance to antimicrobials include

Correct AnswerverifiedShow Answer

Which group are the key drugs used to treat Hansen's disease (leprosy) ?

Correct AnswerverifiedShow Answer

The _____ are drugs that deposit in developing teeth and cause a permanent brown discoloration.

Correct AnswerverifiedShow Answer

Which of the following is not a mode of action of antiviral drugs?

Correct AnswerverifiedShow Answer

Which antimicrobial does not interfere with protein synthesis?

Correct AnswerverifiedShow Answer

Drugs that insert on the _____ ribosomal subunit prevent peptide bond formation or inhibit translocation of the subunit during translation.

Correct AnswerverifiedShow Answer

Which of the following antibacterial drug groups does not target protein synthesis?

Correct AnswerverifiedShow Answer

An antiviral that is a guanine analog would have an antiviral mode of action that

Correct AnswerverifiedShow Answer

Substances that are naturally produced by certain microorganisms that can inhibit or destroy bacteria are called

Correct AnswerverifiedShow Answer

Mebendazole,thiabendazole,and ivermectin are drugs used to treat _____ infections.

Correct AnswerverifiedShow Answer

Which drug is used to treat cases of tuberculosis?

Correct AnswerverifiedShow Answer

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B,then pathogen A will have a/n _____ zone of inhibition compared to pathogen B.

Correct AnswerverifiedShow Answer

Side effects that occur in patient tissues while they are on antimicrobial drugs include all of the following except

Correct AnswerverifiedShow Answer

Each of the following contributes to emerging drug resistance except

Correct AnswerverifiedShow Answer

Which of these drugs has the most narrow-spectrum activity?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Sulfa drugs work on

Correct AnswerverifiedShow Answer

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