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Which statement about RNA processing in eukaryotes is INCORRECT?


A) Introns are simply excised out of pre-mRNA to produce the mature mRNA.
B) A protein/RNA complex is used to remove introns from the pre-mRNA.
C) A poly A tail is added on to the 3' end of the mRNA.
D) A 7-methylguanosine cap is added on to the 5'end of the mRNA.
E) Processing occurs in the nucleus.

F) None of the above
G) B) and E)

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Transcription begins near a site in the DNA called the


A) promoter
B) enhancer
C) response element
D) transcription unit
E) regulatory sequence

F) B) and C)
G) A) and D)

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A

The most common eukaryotic ribosome carries out its function in the


A) Golgi apparatus.
B) nucleus.
C) cytosol.
D) mitochondria.
E) chloroplast.

F) None of the above
G) A) and B)

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What enzyme catalyzes the attachment of amino acids to tRNA molecules?


A) helicase
B) topoisomerase
C) aminoacyl-tRNA synthetase
D) ribosome
E) translation factor

F) B) and E)
G) A) and D)

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An mRNA sequence is 5'AUG-GGC-ACU-CAU-ACU-UAA3'F10,where AUG is the start codon and UAA is the stop codon.How many distinct aminoacyl-tRNA synthetases are required to translate the mRNA sequence?


A) 2
B) 3
C) 4
D) 5
E) 6

F) A) and B)
G) A) and D)

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The transcription process in a eukaryotic gene directly produces


A) rRNA.
B) pre-mRNA.
C) mRNA.
D) DNA.
E) protein.

F) C) and D)
G) A) and E)

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This mRNA transcript would result in what polypeptide sequence? 5'ACU-UUC-ACU-AUG-UUU-UUA-UCC-UCC-ACU-CCU-UGA 3' Use the following codons and the amino acids they encode. AUG = Start or Met;UUU,UUC = Phe;UUA,UUG = Leu;UCU,UCC = Ser;CCU,CCC = Pro;ACU,ACC = Thr;UGA = Stop.


A) Thr-Phe-Thr
B) Phe-Leu-Ser-Ser-Thr-Pro
C) Met-Phe-Leu-Ser-Ser-Thr-Pro
D) Thr-Phe-Thr-Phe-Leu-Ser-Ser-Thr-Pro
E) Met-Phe-Leu-Ser-Ser

F) A) and B)
G) C) and D)

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When does the small ribosomal subunit bind to the translational complex in eukaryotic cells?


A) It is the first component to bind to the mRNA
B) After the initiator tRNA binds,but before the start codon has been found
C) After the large ribosomal subunit binds,but before the initiator tRNA binds
D) After the start codon has been found by initiator tRNA
E) The small ribosomal subunit binds the initiator tRNA and this complex is the first to bind to the mRNA

F) A) and D)
G) B) and C)

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More than one codon can specify the same amino acid.

A) True
B) False

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Which region of a structural gene contains the information that specifies an amino acid sequence?


A) promoter region
B) transcribed region
C) terminator
D) regulatory sequence
E) enhancer region

F) B) and C)
G) A) and C)

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B

Translation is a relatively slow process.

A) True
B) False

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What process enables a single gene to encode two or more polypeptides that are different in their amino acid sequence?


A) Reverse transcription
B) Self-splicing
C) Capping
D) Alternative splicing
E) Regulatory splicing

F) None of the above
G) All of the above

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How many nucleotides are contained in a single codon?


A) 1
B) 3
C) 4
D) 6
E) 9

F) B) and C)
G) B) and D)

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What products of nonstructural genes are never translated?


A) transfer RNA
B) ribosomal RNA
C) messenger RNA
D) transfer RNA and ribosomal RNA
E) ribosomal RNA and messenger RNA

F) A) and C)
G) A) and B)

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When an aminoacyl-tRNA synthetase charges a tRNA it results in the release of which molecule?


A) mRNA
B) ATP
C) AMP
D) pyrophosphate
E) AMP and pryophosphate

F) A) and E)
G) B) and D)

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What serves as the "translator" or intermediary between an mRNA codon and an amino acid?


A) rRNA
B) snRNA
C) tRNA
D) siRNA
E) snRNPs

F) A) and D)
G) B) and E)

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Evaluate the reasons ribosomal genes are useful for comparing evolutionary relationships among organisms?


A) Because there are many differences in these genes,even among closely related species
B) Because all organisms possess these genes and they can be compared with each other
C) Because these are the only genes that have been sequenced for every organism on Earth
D) Because ribosomes of prokaryotes and eukaryotes are identical
E) Because it is possible to compare the large subunit genes with the small subunit genes

F) None of the above
G) B) and E)

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B

The amino acids of a growing polypeptide chain are held together by what kind of bond during the elongation stage of translation?


A) hydrogen
B) peptide
C) glycosidic
D) noncovalent
E) lactose

F) A) and D)
G) B) and D)

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If a DNA template strand has a sequence of 3' TACAATGTAGCC 5',then the RNA produced from it will be


A) 3'TACAATGTAGCC5'
B) 5'ATGTTACATCGG3'
C) 5'AUGUUACAUCGG3'
D) 3'AUGUUACAUCGG5'
E) 3'ATGTTACATCGG5'

F) None of the above
G) All of the above

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What molecule(s) exhibits self-splicing?


A) rRNA
B) tRNA
C) mRNA
D) rRNA and tRNA
E) rRNA and mRNA

F) C) and D)
G) D) and E)

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