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Microorganisms exhibit genomes contained on


A) chromosomes.
B) plasmids.
C) mitochondrial DNA.
D) chloroplast DNA.
E) All of the choices are correct depending on the type of microorganism observed.

F) B) and E)
G) A) and E)

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What type of mutation alters the base but not the amino acid being coded for?


A) Silent
B) Back
C) Point
D) Nonsense
E) Missense

F) B) and C)
G) B) and E)

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The development of virulent,toxin-producing bacterial strains due to the presence of a temperate phage can occur through the process of ________.


A) bacterial conjugation
B) transformation
C) generalized transduction
D) specialized transduction

E) A) and D)
F) A) and B)

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A bacteriophage transfers a random fragment of DNA of the previous host to the current host.This is an example of


A) conjugation.
B) generalized transduction.
C) specialized transduction.
D) the creation of an Hfr cell.

E) None of the above
F) A) and D)

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Which of the following is incorrect about termination codons?


A) They are also called nonsense codons.
B) They are the location where the bond between the final tRNA and the polypeptide is broken.
C) They include AUG.
D) They are UAA, UAG, and UGA.
E) They do not have corresponding tRNA.

F) A) and B)
G) A) and E)

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A mutation has occurred during DNA replication while the cell was preparing to divide.As a result of this,the codon ACU of mRNA has now become ACC.Interestingly,there is no change to the protein being made.Why not?


A) This is a silent mutation.
B) The original amino acid isoleucine was changed to leucine, but they are the same variation of amino acid so no change to the protein.
C) The mutation was fixed, and even though the codon is now ACC the correct amino acid is put into place for the normal protein.
D) This is not a mutation that causes a big change, so there is no change to the protein being made.

E) A) and D)
F) B) and C)

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The _____ is all of the genetic material of a cell.


A) proteome
B) chromosome
C) genome
D) plasmid
E) prophage

F) A) and B)
G) B) and E)

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DNA replication proceeds in one direction around the bacterial chromosome.

A) True
B) False

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The mechanism of DNA synthesis differs between the two new daughter strands during replication.This is due to the fact that


A) both RNA primers attach to the 3'end of the template strands, which are at opposite ends from each other.
B) both daughter strands can't extend toward the replication fork because there would not be room for two DNA polymerase enzymes.
C) one RNA primer attaches to the 5'end of the parent strand and the other primer to the 3'end.
D) the DNA strands run antiparallel to each other and the DNA polymerase can only add nucleotides to the 3' end of the growing strand.

E) B) and C)
F) B) and D)

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Each nucleotide is composed of


A) one phosphate, one nitrogenous base, and one sugar.
B) one phosphate, one nitrogenous base, and two sugars.
C) two phosphates, one nitrogenous base, and one sugar.
D) two phosphates, one nitrogenous base, and two sugars.
E) one phosphate, two nitrogenous bases, and one sugar.

F) A) and B)
G) A) and C)

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Proteomics is the study of all proteins that are expressed by an organism,whereas genomics refers to the study of the organism's entire genome,not simply the protein-coding regions.

A) True
B) False

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Which is incorrect about inducible operons?


A) They have genes turned off by a buildup of end product.
B) They are often for use in catabolic pathways.
C) They are normally turned off.
D) They are turned on by the substrate of the enzyme.
E) They include the lac operon.

F) A) and B)
G) B) and E)

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Erythromcycin,a macrolide,inhibits protein synthesis


A) by interfering with both the initiation and elongation stages of translation.
B) by binding to the tRNA preventing peptide bond formation between amino acids.
C) by preventing the formation of the initiation complex.
D) by binding to the ribosome, preventing translocation due to interference with the attachment of mRNA.

E) A) and B)
F) A) and C)

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DNA polymerase III


A) is needed for adding nucleotides during mRNA synthesis.
B) synthesizes new DNA only in the 5'to 3'direction.
C) cannot add nucleotides to the lagging strand.
D) synthesizes an RNA primer.

E) None of the above
F) A) and B)

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DNA Polymerase I


A) removes primers.
B) adds bases to new DNA chain.
C) seals DNA gaps.
D) proofreads DNA chain.

E) None of the above
F) All of the above

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Which of the following is not a type of bacterial DNA recombination?


A) Transformation
B) Conjugation
C) Mitosis
D) Transduction

E) B) and C)
F) B) and D)

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Structural genes code for


A) ribosomal RNA molecules.
B) transfer RNA molecules.
C) cellular proteins.
D) gene expression elements.

E) None of the above
F) B) and C)

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Repressible operons require that ______ binds to the repressor protein before it can bind to the operator.


A) the product
B) a cofactor
C) a coenzyme
D) the substrate
E) the reactant

F) B) and C)
G) All of the above

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A nucleosome is a linear chromosome wound around the _______.


A) nuclear membrane
B) rRNA
C) mRNA
D) histone
E) nucleolus

F) A) and C)
G) A) and B)

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Replication of DNA begins at a/an _______ rich area.


A) guanine-cytosine
B) uracil-adenine
C) adenine-thymine
D) adenine-cytosine
E) guanine-adenine

F) A) and B)
G) A) and C)

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