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The application of pressure creates a slight electrical charge on osteoblasts.

A) True
B) False

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The type of lamellae found in osteons (Haversian systems) is


A) circumferential.
B) interstitial.
C) appositional.
D) concentric.
E) oppositional.

F) None of the above
G) C) and D)

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Which of the following is correctly matched?


A) periosteum - lines the medullary cavity
B) osteoblasts - break down bone tissue
C) osteoclasts - responsible for reabsorption
D) endosteum - lines central canal of the osteon
E) osteocytes - function in bone remodeling

F) A) and E)
G) A) and B)

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What effects can be attributed to increased pressure on a bone?


A) increased osteoclast activity
B) increased osteoblast activity

C) A) and B)
D) undefined

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Which of the following matrix molecules in cartilage tends to trap large quantities of water?


A) proteoglycan
B) hyaluronic acid
C) elastin
D) collagen
E) chondrocytes

F) A) and E)
G) A) and D)

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Sixty-five year old Stephen has knee replacement surgery which requires a thin section of his distal femur to be removed. Which of the following statements is true?


A) Due to the invasive nature of the surgical procedure, Stephen is at risk for osteomyelitis, a bacterial infection of bone.
B) Stephen has no risk of osteomyelitis because he tests negative for Staphylococcus aureus when given a skin swab.
C) The health care team informs Stephen he is at high risk for osteomyelitis due to his age.
D) As long as the surgery has minimal bleeding, Stephen will have no risk for developing osteomyelitis.

E) None of the above
F) All of the above

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The application of small electrical charges to broken bones are sometimes used to enhance healing.

A) True
B) False

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This figure illustrates bone growth in length at the Epiphyseal Plate. What is zone "B"?


A) zone of calcification
B) zone of proliferation
C) zone of resting cartilage
D) bone of diaphysis
E) zone of hypertrophy

F) C) and D)
G) A) and E)

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This is a diagram of calcium homeostasis. What process is represented by "E"?


A) PTH promotes calcium reabsorption from urine.
B) Vitamin D promotes calcium absorption.
C) Calcium is removed from blood by osteoblasts.
D) Calcium is lost in urine.
E) PTH promotes calcium release into blood by osteoclast.

F) C) and E)
G) A) and D)

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What is the site of long bone growth?


A) endosteum
B) epiphyseal plate
C) medullary cavity
D) periosteum
E) diaphysis

F) A) and B)
G) B) and C)

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How does the urinary system contribute to osteoporosis?


A) Excessive smoking lowers estrogen levels, which increases bone loss.
B) Decreased estrogen levels following menopause contribute to the disease.
C) Immune cells resist infections and release chemicals that promote tissue repair.
D) Calcium ions released from the bones are excreted.
E) Lack of exposure to sunlight reduces vitamin D production and decreases calcium absorption.

F) B) and C)
G) A) and E)

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In which type of bone are osteoblasts and osteoclasts present?


A) spongy bone
B) compact bone
C) both spongy and compact

D) None of the above
E) A) and C)

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Haversian systems or osteons


A) lack concentric lamellae.
B) do not contain osteocytes.
C) are found in spongy bone tissue.
D) are avascular.
E) are the basic units in compact bone tissue.

F) None of the above
G) D) and E)

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Which type of bone cells have processes that lie in canaliculi?


A) osteocytes
B) osteoblasts
C) osteoclasts
D) osteochondral progenitor cell

E) C) and D)
F) None of the above

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What is the membrane that lines the medullary cavity?


A) fibers
B) endosteum
C) growth plate
D) medullary cavity
E) epiphysis

F) C) and D)
G) D) and E)

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Spaces in the bone matrix that are occupied by osteocytes are


A) periosteum.
B) trabeculae.
C) lacunae.
D) lamellae.

E) A) and C)
F) None of the above

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Woven bone


A) has a porous appearance.
B) is not easily restructured.
C) has its collagen fibers randomly oriented.
D) is organized into thin sheets of tissue.
E) is very light in weight.

F) B) and C)
G) A) and D)

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Osteogenesis imperfecta is


A) a disease in adults, especially women, characterized by a reduced amount of bone matrix.
B) a disease in adults characterized by softening of bones resulting from calcium depletion.
C) bone inflammation that often results from bacterial infection.
D) a group of genetic disorders producing very brittle bones that are easily fractured; occurs because of insufficient collagen development.
E) a disease in children characterized by soft, bowed, and swollen bones.

F) B) and E)
G) A) and B)

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The sequence of events that produces growth at the epiphyseal plate is


A) hypertrophy, proliferation, calcification, ossification, and remodeling.
B) hypertrophy, calcification, proliferation, cell death, ossification, and remodeling.
C) proliferation, hypertrophy, calcification, cell death, ossification, and remodeling.
D) calcification, hypertrophy, proliferation, ossification, cell death, and remodeling.
E) proliferation, hypertrophy, cell death, calcification, ossification, and remodeling.

F) A) and B)
G) A) and C)

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A bone fracture generally found in children that is incomplete is a(an)


A) complicated fracture.
B) greenstick fracture.
C) dentate fracture.
D) hairline fracture.
E) spiral fracture.

F) A) and B)
G) None of the above

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