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A positive genetic test for telomerase indicates that


A) RB is inactive.
B) a cell is undergoing apoptosis.
C) proto-oncogenes have not yet mutated.
D) a cell is probably cancerous.
E) tumor suppressors are active.

F) A) and E)
G) All of the above

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A centromere holds together twov: 03_11_2019_QC_CS-162215


A) centrosomes.
B) centrioles.
C) sister chromatids.
D) spindle fibers.
E) non-sister chromatids.

F) D) and E)
G) B) and E)

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Multicellular organisms undergo mitotic cell division to


A) produce new organisms.
B) produce gametes.
C) increase the variability of the population.
D) increase the size of the organism.
E) facilitate sexual reproduction.

F) A) and E)
G) C) and D)

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D

A mutation that causes an increase in function in a tumor suppressor gene would not likely cause cancer because a tumor suppressor protein


A) normally promotes the cell cycle.
B) normally responds to growth factors.
C) activates a signal transduction pathway.
D) inactivates growth factors.
E) does not promote cell division.

F) C) and D)
G) A) and E)

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If you were looking under the compound light microscope at an onion root tip, in what stage of the cell cycle would the majority of the cells be?


A) anaphase
B) metaphase
C) cytokinesis
D) interphase
E) prophase

F) A) and D)
G) A) and E)

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D

In an experiment, cells grown in a petri dish divided until they formed a thin layer covering the bottom of the dish. When cells were removed from the middle of the dish, the cells bordering the open space began dividing until they had filled the empty space. What does this experiment show?


A) When cells come into contact with other cells, they stop growing.
B) The controls on cell growth and division can be turned on and off.
C) Cell division can be regulated by factors outside of the cell.
D) Cells continue to grow as long as there is adequate space.
E) All answers are valid and correct.

F) B) and D)
G) A) and C)

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A proto-oncogene differs from a tumor suppressor gene because a proto-oncogene


A) may cause cancer if mutated, whereas a tumor suppressor gene cannot.
B) stimulates mitosis in a normal cell, whereas a tumor suppressor gene inhibits mitosis.
C) only activates enzymes in a cell that allows metastasis.
D) inhibits the cell cycle, whereas a tumor suppressor accelerates the cell cycle.
E) promotes meiosis, whereas a tumor suppressor gene promotes mitosis.

F) B) and E)
G) C) and D)

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Plant cells and animal cells differ in cytokinesis because


A) plant cells need to build a cell wall, while animal cells do not.
B) animal cells need to build a cell wall, while plant cells do not.
C) animal cells need to build a cell membrane, while plant cells do not.
D) animal cells are living, while plant cells are not.
E) plant cells divide by mitosis, while animal cells divide by meiosis.

F) All of the above
G) A) and B)

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Which lifestyle choice is responsible for 90% of the cases of lung cancer among men?


A) smoking
B) using tanning beds
C) excessive alcohol consumption
D) drug use
E) using smokeless tobacco

F) A) and C)
G) All of the above

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Inheritance of mutant forms of some genes may lead to a predisposition to develop cancer. Which of the genes listed below takes its name from its association with an eye tumor?


A) BRCA1
B) RB
C) RET
D) RAS
E) DScam

F) C) and D)
G) A) and B)

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If there are 20centromeres in a cell, how many chromosomes are there?


A) 10
B) 20
C) 30
D) 40
E) 80

F) B) and E)
G) B) and D)

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A mutation results in a cell that no longer produces a normal protein needed for the M-phase checkpoint. Which of the following would likely be the immediate result of this mutation?


A) the cell would prematurely enter anaphase
B) the cell would never leave metaphase
C) the cell would never enter metaphase
D) the cell would never enter prophase
E) the cell would undergo normal mitosis, but fail to enter the next G 1

F) None of the above
G) B) and D)

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B

Which of the following would increase your risk of cancer?


A) increasing the consumption of foods rich in vitamin A and C
B) avoiding salt-cured, pickled, and smoked foods
C) increasing the consumption of vegetables from the cabbage family
D) avoiding cigarette smoking, smokeless tobacco, and sunbathing
E) avoiding a high-fiber, low-sodium diet

F) B) and D)
G) C) and E)

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If a cell stops at the G 1 checkpoint, this is most likely due to what problem?


A) there is DNA damage
B) the DNA has not finished replicating
C) the chromosomes are not aligned properly
D) the cell is cancerous
E) the chromosomes are not properly attached to the spindle

F) C) and D)
G) A) and E)

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The mitotic spindle is composed of ________, which originate from the __________.


A) microtubules; centrosome
B) asters; spindle equator
C) centrosomes; aster
D) microtubules; chromatid
E) microtubules; cleavage furrow

F) A) and B)
G) A) and C)

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Which of the following occurs prior to prophase?


A) coiling of chromosomes
B) degradation of the nucleolus
C) formation of spindles
D) synthesis of DNA
E) degradation of the nuclear envelope

F) A) and E)
G) A) and B)

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The figure below shows a cell in the mitotic stage of The figure below shows a cell in the mitotic stage of   A)  anaphase. B)  interphase. C)  metaphase. D)  prophase. E)  telophase.


A) anaphase.
B) interphase.
C) metaphase.
D) prophase.
E) telophase.

F) A) and C)
G) A) and E)

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An oncogene is more likely to lead to cancer than a mutant tumor suppressor gene because


A) a gain of function mutation in an oncogene need only occur in one allele before it disrupts control of the cell cycle.
B) a loss of function mutation in an oncogene is sufficient to cause unregulated cell division.
C) the mutant oncogene may inactivate telomerase.
D) a gain of function mutation in a tumor suppressor gene can promote the cell cycle.
E) a gain of function mutation in an oncogene is more likely to cause the other allele to mutate.

F) A) and E)
G) A) and D)

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The drug chloral hydrate prevents elongation of microtubules. During which stage of the cell cycle would chloral hydrate be most harmful?


A) M phase
B) G 1
C) G 2
D) S phase
E) cytokinesis

F) B) and E)
G) A) and D)

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A tumor suppressor gene undergoes a mutation that causes it to lose its normal function. What would be the most likely result of this mutation?


A) the cell cycle halts and reverses back to the G 0 stage
B) the cell loses contact inhibition even when it is not surrounded by other cells
C) the cell cycle accelerates
D) the cell no longer responds to signals that cause it to stop dividing or undergo apoptosis
E) the cell stops dividing permanently and will never re-enter the cell cycle

F) A) and E)
G) A) and D)

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