Question 1

Which of the following is incorrect about prophages?

Accepted Answer

A)   Present when the virus is in lysogeny
B)   Formed when viral DNA enters the bacterial chromosome
C)   Replicated with host DNA and passed on to progeny
D)   Cause lysis of host cells
E)   Occur when temperate phages enter host cellsF) B) and D)
G) B) and C)

Question 2

Virus capsids are made from subunits called ________.

Accepted Answer

A)   envelopes
B)   spikes
C)   capsomeres
D)   prophages
E)   peplomersF) C) and D)
G) C) and E)

Question 3

The development of antiviral drug therapy is difficult because ________.

Accepted Answer

A)   viruses are obligate intracellular parasites so the host cell can be harmed by the drug
B)   viruses do not have specific replication cycles that can be targeted
C)   viruses do not contain genetic material
D)   their life cycles do not have distinctive stagesE) B) and D)
F) B) and C)

Question 4

It is necessary to culture viruses both in vivo and in vitro so that vaccines can be developed, analysis of viral genomes can be made and viruses in clinical specimens can be identified.

Accepted Answer

A) True 
 B)False

Question 5

Viruses have all the following except ________.

Accepted Answer

A)   definite shape
B)   metabolism
C)   genes
D)   the ability to infect host cells
E)   ultramicroscopic sizeF) All of the above
G) D) and E)

Question 6

Satellite viruses are ________.

Accepted Answer

A)   also called viroids
B)   dependent on other viruses for replication
C)   the cause of spongiform encephalopathies
D)   significant pathogens of plants
E)   All of the choices are correctF) A) and C)
G) A) and B)

Question 7

A common method for cultivating viruses in the lab is to use in vitro systems called ________ cultures.

Accepted Answer

A)   embryo
B)   cell
C)   plaque
D)   bacteriophage
E)   eggF) A) and C)
G) A) and B)

Question 8

Viruses are simple, noncellular, and lack ribosomes.

Accepted Answer

A) True 
 B)False

Question 9

Which of the following is not true regarding the structure and function of viral spikes?

Accepted Answer

A)   They are found on both enveloped and naked viruses
B)   They are coded for by the host genome
C)   They are coded for by the viral genome
D)   They mediate the docking process of virus to host cell
E)   They consist of proteins and carbohydratesF) C) and E)
G) B) and D)

Question 10

In general, most DNA viruses multiply in the host cell's ________, while most RNA viruses multiply in the host cell's ________.

Accepted Answer

A)   nucleus; cytoplasm
B)   cytoplasm; cell membrane
C)   cell membrane; cytoplasm
D)   cytoplasm; nucleus
E)   nucleus; endoplasmic reticulumF) C) and D)
G) A) and E)

Question 11

Viruses that cause infection resulting in alternating periods of activity with symptoms and inactivity without symptoms are called ________.

Accepted Answer

A)   latent
B)   oncogenic
C)   prions
D)   viroids
E)   delta agentsF) B) and D)
G) D) and E)

Question 12

Who developed a rabies vaccine by separating bacteria from virus using a filter?

Accepted Answer

A)   Leeuwenhoek
B)   Koch
C)   Pasteur
D)   Cohn
E)   SemmelwiseF) A) and B)
G) C) and E)

Question 13

Viruses mutate and some have not been discovered.

Accepted Answer

A) True 
 B)False

Question 14

Viruses are the most common cause of acute infections that do not result in hospitalization.

Accepted Answer

A) True 
 B)False

Question 15

Which of the following will not support viral cultivation?

Accepted Answer

A)   Live lab animals
B)   Embryonated bird eggs
C)   Primary cell cultures
D)   Continuous cell cultures
E)   All of the choices will support viral cultivation.F) None of the above
G) A) and B)

Question 16

Viral tissue specificities are called ________.

Accepted Answer

A)   ranges
B)   virions
C)   receptacles
D)   tropisms
E)   uncoatingF) A) and B)
G) A) and E)

Question 17

A patient undergoing chemotherapy for cancer develops an infection with cytomegalovirus, conclusively diagnosed by the presence of "owl's eye" viral nuclear inclusions in a liver biopsy. This is an example of a(n)  ________.

Accepted Answer

A)   cytopathic effect by cytomegalovirus
B)   immune response by the host
C)   cytomegalovirus becoming a provirus
D)   transformation of the host cell by cytomegalovirusE) B) and C)
F) A) and B)

Question 18

Respiratory syncytial virus (RSV)  is a common respiratory virus that causes mild cold-like symptoms in most individuals, but can be more serious in infants and the elderly. RSV is so-named because ________.

Accepted Answer

A)   it causes the fusion of damaged host cells, forming a large, multinucleated cell
B)   it causes the proliferation of inclusion bodies within the host cell
C)   it causes a persistent infection in the host
D)   it transforms the host cell, causing cancerE) B) and C)
F) B) and D)

Question 19

Viral spikes are inserted into the host cell membrane before budding or exocytosis.

Accepted Answer

A) True 
 B)False

Question 20

One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n)  ________ capsid.

Accepted Answer

A)   spiked
B)   complex
C)   icosahedral
D)   helical
E)   buckeyballF) B) and D)
G) A) and D)

Exam 5: Viral Structure and Multiplication

Which of the following is incorrect about prophages?

Correct AnswerverifiedShow Answer

Which of the following will not support viral cultivation?

Correct AnswerverifiedShow Answer

Viruses are simple, noncellular, and lack ribosomes.

Correct AnswerverifiedShow Answer

Viruses have all the following except ________.

Correct AnswerverifiedShow Answer

Satellite viruses are ________.

Correct AnswerverifiedShow Answer

Viruses are the most common cause of acute infections that do not result in hospitalization.

Correct AnswerverifiedShow Answer

Viruses that cause infection resulting in alternating periods of activity with symptoms and inactivity without symptoms are called ________.

Correct AnswerverifiedShow Answer

Virus capsids are made from subunits called ________.

Correct AnswerverifiedShow Answer

Respiratory syncytial virus (RSV) is a common respiratory virus that causes mild cold-like symptoms in most individuals, but can be more serious in infants and the elderly. RSV is so-named because ________.

Correct AnswerverifiedShow Answer

A common method for cultivating viruses in the lab is to use in vitro systems called ________ cultures.

Correct AnswerverifiedShow Answer

In general, most DNA viruses multiply in the host cell's ________, while most RNA viruses multiply in the host cell's ________.

Correct AnswerverifiedShow Answer

Viral tissue specificities are called ________.

Correct AnswerverifiedShow Answer

It is necessary to culture viruses both in vivo and in vitro so that vaccines can be developed, analysis of viral genomes can be made and viruses in clinical specimens can be identified.

Correct AnswerverifiedShow Answer

One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n) ________ capsid.

Correct AnswerverifiedShow Answer

Viruses mutate and some have not been discovered.

Correct AnswerverifiedShow Answer

The development of antiviral drug therapy is difficult because ________.

Correct AnswerverifiedShow Answer

A patient undergoing chemotherapy for cancer develops an infection with cytomegalovirus, conclusively diagnosed by the presence of "owl's eye" viral nuclear inclusions in a liver biopsy. This is an example of a(n) ________.

Correct AnswerverifiedShow Answer

Which of the following is not true regarding the structure and function of viral spikes?

Correct AnswerverifiedShow Answer

Who developed a rabies vaccine by separating bacteria from virus using a filter?

Correct AnswerverifiedShow Answer

Viral spikes are inserted into the host cell membrane before budding or exocytosis.

Correct AnswerverifiedShow Answer

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In general, most DNA viruses multiply in the host cell's , while most RNA viruses multiply in the host cell's .

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